 | Stage A: Patients without structural changes, but with a high risk for developing congestive heart failure, are subsumed to stage A. Factors: Risk to develop congestive heart failure. Myocardium, valves and pericardium structurally and functionally uneventful. Possible characteristics: Hypertension, diabetes mellitus, rheumatic fever or cardiotoxic substances in the history, genetic evidence of cardiomyopathies.
Stage B-diagnosis, which includes asymptomatic patients and patients with first structural changes, is equivalent to classification of NYHA-I. Factors: Structural heart disease or reduced ventricular function, no symptoms or signs of congestive heart failure. Possible characteristics: Hypertrophy, dilatation or reduced contractility of the left ventricle, valvular diseases, Infarction-scar.
Stage C defines patients with structural changes and symptoms of congestive heart failure. Also in this stage patients can be judged according to the classes II to IV. Factors: Proof of ventricular dysfunction, actual or history of congestive heart failure. Possible characteristics: Shortening of breath/dyspnea with left-ventricular dysfunction, asymptomatic patient with sufficient treatment of congestive heart failure.
Stage D defines patients with therapy-refractory congestive heart failure. Factors: Terminal end-stage congestive heart failure. Possible characteristics: Hospitalized congestive heart failure-patients, out-patients with mechanical assist devices, palliatively treated end-stag disease patients.
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