Significant risk factors for the development of peripheral arterial occlusive disease are
- Advanced Age
- Systolic Hypertension
- Hyperlipidemia
- Diabetes Mellitus
- Cardiovascular Disease
- Cigarette Smoking
- Physical Inactivity
- Family History of PAD
- Obesity
Microangiopathy is a frequent problem, especially in patients with diabetes.
Furthermore a special type of diffusely calcifying arteriosclerosis (media sclerosis Mönckeberg) is mainly seen in patients with diabetes and/or renal failure.
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